Brain imaging has indicated certain patterns of brain activity are associated with dreaming (and with certain sleep stages where dreams are more likely to occur). It's really hard to study dreaming because people are asleep and we can't observe what's going on. The scientists found that treatment resulted in more deep sleep and more beta-amyloid cleared from the brain.What do scientists know about REM sleep and dreaming? So Ju's team looked to see what happened after patients had been treated successfully for apnea. "And people with sleep apnea are at higher risk for dementia down the line." These patients "seem to have a change in their ability to clear proteins or waste products from their brain," she says. Ju was part of a study of people with obstructive sleep apnea, which repeatedly blocks the airway. Yo-El Ju, an associate professor of neurology at Washington University in St. It's also possible to boost slow waves by treating certain sleep disorders, says Dr. In people, there's some evidence that rhythmic sounds can increase slow waves. "There's a specific deep brain structure that if you stimulate it, you can cause these sleep-like slow waves in the brain," she says. ![]() So now scientists are looking for ways to induce the slow waves that signal deep sleep. What's more, each wave of fluid was preceded by a large, slow electrical wave. "And it was happening at a much larger and slower scale than anything we'd seen during wakefulness." "We realized that there's these waves of fluid flowing into the brain during sleep," she says. In 2019, Lewis led a team that showed how this dishwasher works in people. ![]() "So things like amyloid beta, which are implicated in Alzheimer's disease, seem to actually be removed more rapidly from the brain when an animal is asleep versus when they're awake," says Laura Lewis, an assistant professor of biomedical research at Boston University. In 2013, a landmark study of mice found that their brains switched on a sort of dishwasher during sleep. Shots - Health News Genetically Modified Rat Is Promising Model For Alzheimer's Other studies have found that a lack of deep sleep is associated with higher levels of tau, which forms toxic tangles inside the brain cells of people with Alzheimer's. "We have a specific sleep signature right now that seems to help us better understand where you may sit on the Alzheimer's risk trajectory in the future," Walker says. 2 issue of the journal Current Biology, showed people who got less deep had more beta-amyloid. The scientists used brain scans to monitor levels of beta-amyloid in each participant for up to six years. ![]() None of the participants had memory problems. To find out, Walker's team studied 32 people in their 70s who had taken part in a sleep study that looked for the slow electrical waves that signal deep sleep. So Walker and a team of scientists set out to answer a question: "Can I look into your future and can I accurately estimate how much beta-amyloid you're going to accumulate over the next two years, the next four years, the next six years, simply on the basis of your sleep tonight?" That's when body temperature drops and the brain begins to produce slow, rhythmic electrical waves. The strongest evidence involves deep sleep, he says.
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